Oral Melanotic Macule: Symptoms and Treatment Skinsight Moles (melanocytic naevi, pigmented nevi) Macro shot of benign skin lesion. Proliferation of pigment derma cells, melanocytic pigmented naevus, naevocytic nevus. Mole or melanoma black color Stock Photo Alamy Pathology Outlines Melanotic macule In the 1990s, researchers at the University of Arizona were testing Melanotan II as a tanning agent. During clinical trials, they noticed something unexpected: the compound was causing spontaneous erections in male Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360